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International Journal of Advanced Biomedicine
               
 
 
 
 
 
 
 
 
 
 
 
 

Forthcoming
 

 

Hyperthermic effects of cobalt ferrite nanoparticls on adipose cells

R. A. Hassan,
Abstract :
Abstract: Hyperthermia therapy is a medical treatment based on the exposition of body tissue to slightly higher temperatures than physiological to damage and kill cells. Magnetic nanoparticles possess unique properties which can be applied in nanomedicine, they address targets such as cellular therapy, tissue repair, nanobiosensors, drug delivery, magnetic resonance imaging and magnetic fluid hyperthermia. In this work, cobalt ferrite nanoparticls (CFNP) were selectively synthesized with narrow size distribution using chemical precipitation methods. The obtained powder was calcined at 600 C. The sample which characterized by Transmission Electron Microscopy (TEM)confirmed the formation of single-phase CFNP in the range 1025 nm. Localized magnetic particle hyperthermia treatment using ferrimagnetic nanoparticles continue to be an active area of medical research. So, homemade induction heater was designed. The coil was designed to be capable of generating high frequency, strong alternative magnetic fields. The CFNP hyperthermia application in medical was in vitro studied using samples of rabbits Subcutaneous adipose cells. The adipose cells microscopic imaging data as well as the bio distribution results of hyperthermic CFNP content sample showing decreasing the number of subcutaneous adipocyte cell by 23.9 %. In conclusion the preliminary new results for nanoparticles bearing a CFNP core justify further investigations towards potential hyperthermia slimming applications.

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