Login New user?  
01-Applied Mathematics & Information Sciences
An International Journal


Volumes > Volume 07 > No. 4


AND-NOT logic framework for steady state analysis of Boolean network models

PP: 1263-1274
Alan Veliz-Cuba, Kristina Buschur, Rose Hamershock, Ariel Kniss, Esther Wolff, Reinhard Laubenbacher,
In this paper we propose the class of AND-NOT networks for modeling biological systems and show that it provides several advantages. Some of the advantages include: Any finite dynamical system can be written as an AND-NOT network with similar dynamical properties. There is a one-to-one correspondence between AND-NOT networks, their wiring diagrams, and their dynamics. Results about AND-NOT networks can be stated at the wiring diagram level without losing any information. Results about AND-NOT networks are applicable to any Boolean network. We apply our results to a Boolean model of Th-cell differentiation.

  Home   About us   News   Journals   Conferences Contact us Copyright naturalspublishing.com. All Rights Reserved