|
|
 |
| |
|
|
|
Mathematical Analysis of Virus Dynamics Model with Multitarget Cells in Vivo |
|
|
|
PP: 75-80 |
|
|
|
Author(s) |
|
|
|
Ahmed Bakr,
Ahmed Elaiw,
Z. Raizah,
|
|
|
|
Abstract |
|
|
| This paper investigates the qualitative behavior of viral infection model with multitarget cells in vivo. The infection rate is
given by Crowley-Martin functional response. By assuming that the virus attack n classes of uninfected target cells, we study a viral
infection model of dimension 2n+1 with discrete delay. To describe the latent period for the contacted target cells with viruses to
begin producing viruses, two types of discrete delay are incorporated into the model. The basic reproduction number R0 of the model
is defined which determines the dynamical behaviors of the model. Utilizing Lyapunov functionals and LaSalle’s invariance principle,
we have proven that if R0 ≤ 1 then the uninfected steady state is globally asymptotically stable, and if R0 > 1 then the infected steady
state is globally asymptotically stable. |
|
|
|
|
|
|
|
